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S-Nitroso-L-glutathione

Releases nitric oxide spontaneously under physiological conditions and plays an essential role in the biochemical and physiological functions of nitric oxide pathways.

Product Attributes

CAS number

57564-91-7

Molecular weight

336

Storage Conditions

Store at -10 to -35 °C, Desiccate

Molecular Formula: C10H16N4O7S

Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
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Protocols
SDS

Product Description

Similar to SNAP, S-nitrosogluthathione (SNOG or GSNO) releases nitric oxide (NO) spontaneously under physiological conditions and plays an essential role in the biochemical and physiological functions of NO pathways.

  • Generate nitric oxide and superoxides
  • Pinkish solid soluble in water and DMSO

NO concentration is often assessed by measuring nitrite level using the Griess Reagent. If a variety of nitric oxide generators are needed, we offer a Nitric Oxide Generation Kit which has 10mg each of SIN-1 (00221), SNAP (00222), S-nitrosoglutathione (00223), spermine NONOate (00224), and DEA-NONOate (00225).

Molecular Structure:

References

  1. Biochemistry 34, 7177 (1995), DOI: 10.1021/bi00021a032
  2. Br J Pharmacol 107, 745 (1992), DOI: 10.1111/j.1476-5381.1992.tb14517.x
  3. Chem. Res. Toxicol. 23, 2 (2010), DOI: 10.1021/tx900387k
 

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