Fluorescent Proteins, Nucleotides & Other Conjugates

5-Aminoallyl-UTP can be enzymatically incorporated into RNA for subsequent labeling with an amine-reactive fluorescent dye, biotin, or other hapten.

5-Aminoallyl-dUTP (AA-dUTP) can be enzymatically incorporated into DNA. The resulting amine-containing DNA can be subsequently labeled with a fluorescent dye, biotin or other haptens via conventional peptide coupling method.

Fluorescent CF® dye hydrazides are bright, extremely water-soluble, nontoxic molecules, useful as aldehyde-fixable cell tracers. They can also be used to label aldehyde or ketone groups of polysaccharides, carbohydrates or glycoproteins.

CF® Dye biocytin is a cell-impermeant, fixable polar tracer that is a conjugate of CF® Dye and biotin with an aldehyde-fixable primary amine. Polar tracers are commonly used to investigate cell-cell and cell-liposome fusion as well as membrane permeability and transport through gap junctions or cell uptake during pinocytosis.

PNA lectin is a widely used histological fluorescent stain and is labeled with our superior CF® Dyes. It is specific for terminal β-galactose and binds preferentially to the commonly occurring structure, galactosyl (β-1,3) N-acetylgalactosamine.

CF®DI dye hydrazides react with carbonyl moieties of aldehyde or ketone groups. They are size- and charge-matched for detection of protein carbonylation by fluorescence two-dimensional differential gel electrophoresis (2D-DIGE).

Fluorescent dUTP can be used to synthesize labeled DNA probes for in-situ hybridization, microarray or blotting techniques.

CF® Dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 10,000 MW, and contains a formaldehyde-fixable free-amine group.

CF® dye dCTP can be used to synthesize labeled DNA probes for in-situ hybridization, microarray or blotting applications.

TS biotin ethylenediamine (Biotin ethylenediamine thiosulfate, sodium salt) is a highly selective thiol labeling probe. Similar to the MTS group, TS (thiosulfate) group is capable of reacting with thiols at nearly neutral pH.

The CF® dye TUNEL Assay Apoptosis Detection Kit label apoptotic cells in fixed tissue sections or cellular samples for fluorescence microscopy or flow cytometry.

Labeled with our superior CF® dyes, dUTP conjugates can be used for TUNEL assay or to synthesize labeled DNA probes for in situ hybridization and nucleic acid blotting applications.

MTSEA biotin selectively labels thiols under mild conditions. It’s available in 3 variations: Biotin, Biotin-X, and Biotin-XX, all of which allow selective labeling of cell surface thiols.

Near-IR Annexin V fluorescent conjugates can be used to detect apoptotic cells and are suitable for in vivo imaging.

Fluorescently labeled cAMP analogs that can be used to probe cAMP receptors.

Labeled human transferrin is used for microscopic studies of the endosomal pathway and/or transferrin uptake studies.