CELLDATA DNAstorm™ 2.0 MagBead FFPE DNA Extraction Kit
A magnetic bead-based kit for superior DNA extraction from FFPE samples. Features proprietary technology for enhanced removal of formaldehyde-induced damage, providing DNA with higher yield and greater amplifiability.
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Product Description
Formalin-fixed tissue samples are a challenge for DNA extraction, often resulting in low yields and poor performance in subsequent steps. Most existing methods rely on heat to remove crosslinks and adducts, which is only partially effective and leads to additional fragmentation of labile nucleic acids. Powered by proprietary CAT5™ technology, the DNAstorm™ 2.0 MagBead FFPE Extraction Kit enhances the removal of formaldehyde-induced damage and provides DNA with higher yield and quality and greater amplifiability. The DNAstorm™ 2.0 MagBead FFPE DNA Extraction Kit is the best solution for next-generation sequencing and other advanced applications. This kit uses magnetic beads for DNA isolation and may be adapted for multiwell plate format. For spin column-based DNA purification, see our original CELLDATA DNAstorm™ 2.0 FFPE DNA Extraction Kit.
- Purify higher quality DNA with less fragmentation
- Extract higher yields of amplifiable DNA compared to other methods
- CAT5™ technology for chemical reversal of formaldehyde crosslinking
- Milder conditions and no harsh solvents
- Better results in downstream analysis like PCR, microarray, or next-generation sequencing
- Magnetic bead-based DNA purification adaptable for multiwell plate formats
Note: This kit is a magbead-based version of catalog number CD502 that uses a modified deparaffinization protocol with a new Dewaxing Solution (provided in the kit). The new kit retains the same proprietary CAT5™ catalytic technology for highly efficient reversal of formaldehyde crosslinks as the original kit.
The DNAstorm™ 2.0 DNA extraction kit greatly accelerates the removal of formaldehyde damage and allows recovery of higher quality nucleic acids. This results in higher yields, more intact DNA, and better results in downstream analysis like PCR, microarray, or next-generation sequencing (NGS). We also offer the CELLDATA RNAstorm™ 2.0 FFPE RNA Extraction Kit (CD506) for extraction of high-quality RNA from FFPE tissue samples. The RNAstorm™ and DNAstorm™ kits can be combined to obtain both pure DNA and RNA from the same tissue section. See our DNAstorm™/RNAstorm™ 2.0 FFPE Combination Kit (CD508) which includes the RNAstorm™ 2.0 kit (CD506) and DNAstorm™ 2.0 kit (CD507). For a detailed protocol please see our App Note – Dual DNA and RNA Extraction From a Single FFPE Sample.
RNAstorm™ and DNAstorm™ FFPE Extraction Kits
Product Name | Catalog Number | Size |
---|---|---|
CELLDATA RNAstorm™ 2.0 FFPE RNA Extraction Kit | CD506 | 50 preps |
CELLDATA DNAstorm™ 2.0 FFPE DNA Extraction Kit | CD507 | 50 preps |
CELLDATA DNAstorm™/RNAstorm™ 2.0 Combination Kit | CD508 | 50 preps |
CELLDATA DNAstorm™ 2.0 MagBead FFPE DNA Extraction Kit | CD509-96 | 96 preps |
References
- Am J Surg Pathol, 43, 1720 DOI: 10.1097/PAS.0000000000001338