CD5 Monoclonal Mouse Antibody (B-B8)
Wishlist updated! View wishlist
Product Description
This antibody recognizes a 67 kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this MAb is not suitable for frozen tissues.
References
Note: References for this clone sold by other suppliers may be listed for expected applications.
- Inf Immunity (1996) 64(5): 1595-1599. (cell depletion)
- Br J Haematol (2013) 163: 182-193. (antibody internalization)