Support & Resources

+1

CD26 Monoclonal Mouse Antibody (134-2C2)

Recognizes a glycoprotein of 110 kDa, identified as CD26.

Product Attributes

Antibody number

0162

Reactivity (target)

CD26

Antibody type

Primary

Host species

Mouse

Clonality

Monoclonal

Clone

134-2C2

Isotype

IgM, kappa

Molecular weight

~110 kDa

Human gene symbol

DPP4

Entrez gene ID

1803

SwissProt

P27487

Unigene

368912

Immunogen

A synthetic peptide from the amino terminal region of CD26

Cellular localization

Membrane/cell surface

Species reactivity

Human

Applications

Immunofluorescence, Flow cytometry, Immunohistology (frozen)

Application notes

Immunohistology Frozen Only 0.5-1.0 ug/mL, Immunofluorescence 0.5-1 ug/mL, Flow Cytometry 0.5-1 ug/million cells/0.1 mL, Optimal dilution for a specific application should be determined by user

Positive control

U-87 MG (Human glioblastoma astrocytoma), Ramos (Human Burkitt's lymphoma, HEP-G2 cells, and lymphocytes. Lymph nodes and tonsils.

Shipping condition

Room temperature

Storage Conditions

Store at 2 to 8 °C, Note: store BSA-free antibodies at -10 to -35 °C

Shelf life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Regulatory status

For research use only (RUO)

Research areas

Immunology

Cell/tissue expression

Epithelial cells

Conjugation
Don’t see what you’re looking for? Contact us for more conjugation options.
Size
Catalog #
price
Qty
50 uL
100 uL
250 uL
500 uL
Clear selection
Add to wishlist
ADD TO CART
(Please select quantity above )

Wishlist updated! View wishlist

Shipping, Handling & Tax (CA only) not included in price. Learn more

Tax is assessed in the state of California. All fees will be calculated during checkout based on your shipping information and are subject to change.

SPECIAL - Order 5 or more and receive 10% off.

Request a Bulk Quote

Product Description

Recognizes a glycoprotein of 110 kDa, identified as CD26. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.

This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

References

Fleischer B. CD26: a surface protease involved in T-cell activation. Immunol Today 1994, 15(4):180-184. | Abbott CA. et. al. Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidyl peptidase IV) gene. Immunogenetics 1994, 40:331-338. | Valenzuela A et. al. HIV-1 envelope gp120 and viral particles block adenosine deaminase binding to human CD26. Adv Exp Med Biol 1997, 421:185-192. | Cheng HC, et al. Lung endothelial dipeptidyl peptidase IV promotes adhesion and metastasis of rat breast cancer cells via tumor cell surface-associated fibronectin. J Biol Chem. 1998 273(37):24207-24015

 

You may also like…