Monoclonal anti S100A9 (S100A9/1075)

string(39) "$120.00"
Clear selection
Catalog #: BNUB1075
 Multiple sizes
Category: .
>>> Order 5 or more and receive 10% off.

Product Description

This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer’s cells of the liver and Langerhan’s cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

Hsu SM et al. American Journal of Pathology. 138(6):1389-404 (1991)

Additional Information


Purified with BSA, 0.2 mg/mL, Purified, BSA-free, 1 mg/mL, CF405S, CF405M, CF488A, CF543, CF555, CF568, CF594, CF640R, CF647, CF660R, CF680, CF680R, CF770, Biotin, R-PE, APC, Per-CP, Alkaline Phosphatase, HRP


50 uL, 100 uL, 250 uL, 500 uL

Supplied As

Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide, Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA

Antibody type


Host species


Reactivity (target)

S100A9 (S100A9/1075)






IgG2b, kappa

Molecular weight

14 kDa

Entrez gene ID





Recombinant human S100A9 protein



Species reactivity

Human, Rat


Flow cytometry, Immunofluorescence, Immunohistology (formalin)

Cellular localization

Cytoplasmic, Extracellular (secreted) and Cell Surface

Application notes

Flow Cytometry (0.5-1 ug/million cells/0.1 mL), For staining of formalin-fixed, paraffin-embedded tissues, digest with trypsin at 1mg/mL PBS, 15 min at RT, Immunofluorescence 0.5-1 ug/mL, Immunohistology formalin-fixed 0.5-1 ug/mL for 30 minutes at RT

Positive control

Liver or histiocytoma

MSDS (PDF):MSDS Primary antibodies

Protocol (PDF): Protocols for antibody-based detection

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

Expedited shipment may be requested at time of checkout.

Please note that products with recommended storage at 4°C or -20°C may ship at ambient temperature. This will not affect product performance. When you receive the product, place it under the recommended storage conditions.

More information about product handling and shelf life