Monoclonal anti TGF beta (1D11.16.8)

string(39) "$120.00"
Clear selection
Catalog #: BNUB0977
 Multiple sizes
Category: .
>>> Order 5 or more and receive 10% off.

Product Description

This MAb recognizes TGF beta 1, 2 and 3. Three TGF? ?s have been identified in mammals. TGF? ?1, TGF? ?2 and TGF? ?3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF? ? requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF? ?3 protein has approximately 80% identity to the mature region of both TGF? ?1 and TGF? ?2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGF? ?’s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.

Dasch JR, Pace DR, Waegell W, Inenaga D, Ellingsworth L. Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification. J Immunol. 1989 Mar 1;142(5):1536-41

Additional Information


Purified with BSA, 0.2 mg/mL, Purified, BSA-free, 1 mg/mL, CF405S, CF405M, CF488A, CF543, CF555, CF568, CF594, CF640R, CF647, CF660R, CF680, CF680R, CF770, Biotin, R-PE, APC, Per-CP, Alkaline Phosphatase, HRP


50 uL, 100 uL, 250 uL, 500 uL

Supplied As

Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide, Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA

Antibody type


Host species


Reactivity (target)

TGF-beta (1D11.16.8)






IgG1, kappa

Molecular weight

~13 kDa

Entrez gene ID

7040 (beta1), 7042 (beta2) & 7043 (beta3)


P01137 (beta1), P10600 (beta2) & P61812 (beta3)


Bovine TGF-beta2 protein



Species reactivity

Cow, Dog, Hamster, Human, Monkey, Mouse, Rat



Cellular localization

Cytoplasm and extracellular (secreted)

Application notes

Cytokine neutralization or functional assay, order Ab without BSA/azide, Optimal dilution for a specific application should be determined

Positive control

Salivary gland carcinoma

MSDS (PDF):MSDS Primary antibodies

Protocol (PDF): Protocols for antibody-based detection

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

Expedited shipment may be requested at time of checkout.

Please note that products with recommended storage at 4°C or -20°C may ship at ambient temperature. This will not affect product performance. When you receive the product, place it under the recommended storage conditions.

More information about product handling and shelf life