Polyclonal anti UPK3A (Uroplakin 3A) (Rabbit PAb)

BNUB0409-0
string(39) "$120.00"
Price:
 from
  $120.00
Clear selection
Catalog #: BNUB0409
Selection:
 Multiple sizes
Category: .
>>> Order 5 or more and receive 10% off.

Product Description

Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Lai Y et. al. 2010. UPK3A: a promising novel urinary marker for the detection of bladder cancer. Urology 76, 514; 2009

Additional Information

Applications

Flow cytometry, Immunofluorescence, Western

Conjugation

Purified with BSA, 0.2 mg/mL, Purified, BSA-free, 1 mg/mL, CF405S, CF405M, CF488A, CF543, CF555, CF568, CF594, CF640R, CF647, CF660R, CF680, CF680R, CF770, Biotin, R-PE, APC, Per-CP, Alkaline Phosphatase, HRP

Size

50 uL, 100 uL, 250 uL, 500 uL

Supplied As

Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide, Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA

Antibody type

Primary

Host species

Rabbit

Reactivity (target)

UPK3A (Uroplakin 3A) (Rabbit PAb)

Clonality

Polyclonal

Isotype

IgG

Clone

Rabbit PAb

Molecular weight

~30 kDa

Synonyms

UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A

Entrez gene ID

7380

SwissProt

O75631

Unigene

632787

Immunogen

A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Species reactivity

Human

Cellular localization

Cell surface

Application notes

Flow Cytometry (0.5-1 ug/million cells/0.1 mL), Immunofluorescence 1-2 ug/mL, Optimal dilution for a specific application should be determined by user, Western blotting 0.5-1 ug/mL

Positive control

HEK293 cells or bladder carcinoma

MSDS (PDF):MSDS Primary antibodies

Protocol (PDF): Protocols for antibody-based detection

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

Expedited shipment may be requested at time of checkout.

Please note that products with recommended storage at 4°C or -20°C may ship at ambient temperature. This will not affect product performance. When you receive the product, place it under the recommended storage conditions.

More information about product handling and shelf life