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ViaFluor® Live Cell Microtubule Stains

Cell-permeant TAXOL®-based probes for imaging the microtubule cytoskeleton in live cells. Available with blue, green, or far-red fluorescence.

Product Attributes

Dye

ViaFluor® 405, ViaFluor® 488, ViaFluor® 647

Cellular localization

Cytoskeleton, Microtubules

Cell permeability

Membrane permeant

For live or fixed cells

For live/intact cells

Assay type/options

Long term staining (24-72h)

Colors

Blue, Green, Far-red

Concentration

1000X in DMSO

Storage Conditions

Store at 2 to 8 °C, Protect dye component from light

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Dye
Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
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Trial size (10 uL)
50 uL
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Product Description

ViaFluor® Live Cell Microtubule Stains are cell-permeant TAXOL® (paclitaxel) probes for imaging the microtubule cytoskeleton in live cells. They are simple, rapid and sensitive stains that can be imaged without a wash step.

  • Cell-permeant fluorescent microtubule probes
  • Rapid, sensitive, no-wash stains for live cells
  • Available with blue, green, or far-red fluorescence
  • ViaFluor® 647 dye compatible with SIM or STED

TAXOL® binds to polymerized tubulin and stabilizes microtubules, resulting in inhibition of mitosis. However, fluorescent TAXOL® compounds like ViaFluor® Microtubule Stains are less disruptive of microtubule dynamics and cell division, presumably due to lower binding affinity of the fluorescent probe compared to TAXOL® itself. The probes can be used to stain cells for as long as 48 hours to several days. However, the probes may show cytotoxicity and cell cycle arrest with longer incubation times. The stains are supplied as a 1000X stock solutions in DMSO, and include a vial of 100 mM verapamil, an efflux pump inhibitor that may improve probe retention and staining in some cell types.

ViaFluor® Live Cell Microtubule Stains cannot be fixed after staining, and cannot be used with fixed cells or tissues. The probes are not predicted to bind bacterial or yeast microtubules. Learn more about our other Fluorescent Cellular Stains for nucleus, mitochondria, lysosomes, or see our selection of Microbiology Stains & Kits.

 

ViaFluor® Live Cell Microtubule Stains

DyeEx/EmCatalog no.Size (1000X
in DMSO)*
Features
ViaFluor® 405 408/452 nm70064-T10 uLBlue fluorescence for the DAPI channel
7006450 uL
ViaFluor® 488500/515 nm70062-T10 uLGreen fluorescence for the FITC channel
7006250 uL
ViaFluor® 647650/675 nm70063-T10 uLFar-red fluorescence for the Cy®5 channel
Compatible with SIM or STED
7006350 uL
* Supplied with 100 mM verapamil in DMSO for optional use.
Cy5 is a registered trademark of GE Healthcare. TAXOL is a registered trademark of Bristol-Myers Squibb.
 

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