Cell & Organelle Stains

Similar to other sulforhodamine dyes, the highly water-soluble sulforhodamine G can also be used as a polar tracer for the studies of cell morphology and neuronal cell-cell communication (1-3).

Tetrabromorhodamine 123 can be used to generate singlet oxygen (¹O₂) in mitochondrial membranes (1,2). The dye has a quantum yield for singlet oxygen generation of 0.65-0.7 and is particularly toxic to carcinoma cells.

This toxin reversibly blocks the sodium channels of neurons and has been a widely used tool for mechanistic studies of neurons, skeletal muscle, and cardiac muscle cells.

Texas Red®-DHPE is a rhodamine-labeled glycerophosphoethanolamine lipid.

TMR biocytin is a cell-impermeant, fixable polar tracer that combines the tetramethylrhodamine (TAMRA) with biotin and an aldehyde-fixable primary amine.  Polar tracers are commonly used to investigate cell-cell and cell-liposome fusion as well as membrane permeability and transport through gap junctions or cell uptake during pinocytosis.

TMRE (Tetramethylrhodamine ethyl ester, perchlorate) and TMRM (70017) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.

TMRE (Tetramethylrhodamine ethyl ester, perchlorate) is used to quantify changes in mitochondrial membrane potential in live cells.

TMRM (Tetramethylrhodamine methyl ester, perchlorate) and TMRE are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.

TRITC-DHPE  is a rhodamine-labeled glycerophosphoethanolamine lipid. DHPE conjugates of rhodamine dyes have been used in membrane fusion assays.