DNA Binding Dyes

The amine reactive succinimidyl ester of MB (methylene blue) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups.  The conjugate will have a blue color and be able to complex with nucleic acids.

A commonly used redox indicator in nucleic acid research. MB-Azide can be used to label alkyne, BCN, or phosphine-containing molecules.

A commonly used redox indicator in nucleic acid research. MB-dibenzocyclooctyne (DBCO) allows copper-free bioorthogonal conjugation to spontaneously label molecules containing azide groups.

A commonly used redox indicator in nucleic acid research. MB-Maleimide can be used to label molecules containing free thiol groups.

A commonly used redox indicator in nucleic acid research. MB-methyltetrazine may be used to label TCO (trans-cyclooctene) tagged molecules via a copper-free reaction.

A commonly used redox indicator in nucleic acid research. MB-TCO (trans-cyclooctene) may be used to label tetrazine tagged molecules via a copper-free reaction.

Thiazole Green, which is structurally identical to SYBR® Green I Nucleic Acid Gel Stain, is one of the most sensitive stains available for detecting double-stranded DNA (dsDNA) in agarose, polyacrylamide gels and qPCR.

Thiazole Orange Homodimer (TOhD), also known as TOTO®-1, is a cell-impermeant, high-affinity, fluorogenic green nucleic acid stain.

Thiazole orange (TO) is commonly used in reticulocyte analysis to stain residual RNA of blood cells, to stain DNA in agarose gels and capillary electrophoresis. Thiazole Orange stains the yeast nucleus, and is also able to stain bacteria and mammalian cells.

Thiazole Red, also known as TO-PRO®-3, is a cell-impermeant, high-affinity far-red nucleic acid stain.

Thiazole red homodimer (TRhD), also known as TOTO®-3, is a cell-impermeant, high-affinity, far-red fluorogenic nucleic acid stain.

The amine reactive succinimidyl ester of TO (thiazole orange) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups.  The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in green fluorescence.

DAPI is a popular blue fluorescent DNA dye. The dye binds to the minor groove of dsDNA with approximately 20-fold fluorescence enhancement.

A high purity grade, red fluorescent nucleic acid dye for detecting nucleic acids in solution or for selectively staining dead cells with damaged plasma membranes.

6X DNA loading buffer that includes ultra-sensitive, non-toxic GelRed® dye.

7-AAD (7-aminoactinomycin D) is a membrane-impermeant fluorescent DNA binding dye that is useful for live/dead discrimination and cell cycle profiling by flow cytometry.