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Fluorescein Methotrexate, Triammonium Salt

Fluorescein methotrexate is useful for studying anti-metabolite resistance and spontaneous gene amplification. The dye is actively taken up by cells and binds to dihydrofolate reductase (DHFR) quantitatively.

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Product Description

Fluorescein methotrexate is useful for studying anti-metabolite resistance and spontaneous gene amplification. The dye is actively taken up by cells and binds to dihydrofolate reductase (DHFR) quantitatively.

  • λExEm = 496/516nm
  • Yellow solid soluble in pH>6.5 buffer, DMF or DMSO
  • Store desiccated at 4°C and protect from light
  • C46H54N14O9S
  • MW:979.08

 

References

1. J Cell Biol 162, 23 (2003).

2. Nat Biotechnol 19, 769-772 (2001).

3. J Biol Chem 257, 14162 (1982).

 

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